Drug intelligence / Profile preview

moderate neuromuscular blockade-Kuala Lumpur General Hospital

Development stage
Unknown
Lead developer
Organon
Modality
Small Molecules
01

Overview

Moderate neuromuscular blockade-Kuala Lumpur General Hospital refers to a specific clinical trial intervention arm (NCT02794714) conducted at Kuala Lumpur General Hospital. This regimen involves the administration of rocuronium, a non-depolarizing neuromuscular blocking agent, to achieve a moderate depth of muscle relaxation (defined by a Train of Four Count of 2) during laparoscopic gynecological surgeries. The protocol also includes the subsequent reversal of the blockade using sugammadex, a selective relaxant binding agent. The trial compares this moderate blockade level against deep neuromuscular blockade to evaluate surgical operating conditions and patient satisfaction.

Other names
Moderate neuromuscular blockade
02

Targets

Nicotinic Acetylcholine Receptor

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