modified Changpu Yujin Tang

Modified Changpu Yujin Tang is a Traditional Chinese Medicine (TCM) herbal formulation developed and utilized by researchers at Tianjin Huanhu Hospital for the treatment of convulsive status epilepticus (CSE). The formula is a modification of the classic Changpu Yujin Tang, which traditionally contains *Acorus tatarinowii* (Shichangpu) and *Curcuma aromatica* (Yujin). In the context of CSE, the modification typically involves the addition of herbs such as *Arisaema cum Bile* (Dan Nan Xing) and *Bambusae Caulis in Taeniam* (Zhu Ru) to enhance its ability to clear heat, resolve phlegm, and open the orifices. Pharmacologically, the decoction is thought to exert anticonvulsant and neuroprotective effects by modulating neurotransmitter systems—specifically increasing GABAergic inhibition and reducing glutamatergic excitotoxicity—and by suppressing neuroinflammatory cytokines like IL-6 and TNF-alpha. It is generally administered as an adjunctive therapy alongside standard Western anti-epileptic drugs to improve consciousness recovery and reduce seizure recurrence.

Other names

Jiajian Changpu Yujin TangModified Acorus and Curcuma DecoctionModified Changpu Yujin Decoction