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Modified Dachaihu Decoction is a Traditional Chinese Medicine (TCM) herbal formulation derived from the classic Da Chai Hu Tang formula. It is specifically developed and investigated by the Quanzhou Traditional Chinese Medicine Hospital for its potential to promote ovulation in women with Polycystic Ovary Syndrome (PCOS), particularly those presenting with the TCM pattern of Liver-Meridian Heat. The decoction typically consists of a blend of herbs including Bupleurum, Scutellaria, and Rhubarb, which are traditionally used to clear heat and harmonize the liver and gallbladder. In clinical research, it is used as an adjunct to intrauterine insemination (IUI) cycles to improve follicular maturation and clinical pregnancy rates by potentially regulating the hypothalamic-pituitary-ovarian axis and improving metabolic dysfunction.
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