Drug intelligence / Profile preview

modified Danggui Buxue Decoction

Development stage
Unknown
Lead developer
Gansu Provincial Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Modified Danggui Buxue Decoction is a Traditional Chinese Medicine (TCM) herbal formulation being evaluated for the treatment of knee osteoarthritis and degenerative bone and joint diseases. It is a variation of the classic Danggui Buxue Decoction, which is traditionally composed of *Astragalus membranaceus* (Huangqi) and *Angelica sinensis* (Danggui) in a 5:1 ratio. The modification involves the addition of other medicinal herbs to specifically target joint pain, inflammation, and bone health. The decoction is being studied by the Gansu Provincial Hospital of Traditional Chinese Medicine as part of a clinical research program to establish evidence-based guidelines for TCM in orthopedics. It is typically administered orally as a liquid extract.

Other names
modified Danggui Buxue TangJiajian Danggui Buxue Tangmodified Dang-Gui-Bu-Xue-Tang
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))IL1B (Interleukin-1 beta)

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