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Modified Huangfeng Decoction
- Development stage
- Preclinical
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- Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
- Administration
- Oral
01
Overview
Modified Huangfeng Decoction is a traditional Chinese medicine (TCM) herbal formula that has been adapted from the classical "Huangfeng" decoction. It is used primarily in China for its multitarget effects, including the alleviation of diabetic nephropathy and improvement of long-term prognosis in patients with systemic lupus erythematosus complicated by antiphospholipid antibody syndrome. Mechanistically, it has been shown to activate autophagy and regulate gut microbiota, contributing to renal protection and immunomodulation[1][2]. The specific herbal composition may vary depending on clinical context, as is common with modified TCM formulas.
- Brand names
- Modified Huangfeng Decoction
02
Targets
mTOR (Mammalian target of rapamycin kinase)
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