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Modified Liujunzi Decoction
- Development stage
- Preclinical
- Administration
- Oral
01
Overview
Modified Liujunzi Decoction (MLJZT) is a Chinese herbal medicine formula used as an adjunct therapy during chemotherapy for patients with advanced non-small cell lung cancer (NSCLC). It has been evaluated for its efficacy and safety in alleviating chemotherapy-induced anorexia and reducing weight loss. A propensity score-matched case-control study indicated that MLJZT was effective in improving anorexia and mitigating weight reduction in patients receiving cisplatin-based chemotherapy, without increasing the incidence of side effects such as hematological and hepatorenal toxicity. These findings suggest its potential as a supportive care option in cancer treatment.
- Other names
- Modified Liujunzi Decoction (加味六君子汤)
02
Targets
IL-6 (Interleukin 6)PIK3R1 (Phosphoinositide-3-kinase regulatory subunit 1)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)
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