modified Ma Xing Shi Gan Decoction

Modified Ma Xing Shi Gan Decoction is a traditional Chinese medicine (TCM) polyherbal formulation being evaluated for the treatment of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). This specific modification, studied by investigator Cuiling Feng, is based on the classic Ma Xing Shi Gan Decoction—originally consisting of *Ephedra sinica*, *Prunus armeniaca*, *Gypsum fibrosum*, and *Glycyrrhiza uralensis*—and is tailored to address the 'Lung-Large Intestine Mutual Interior-Exterior Relationship' theory. The formula is intended to clear lung heat, resolve phlegm, and relieve dyspnea by modulating systemic and local inflammation. In clinical trials, it is administered as an oral decoction in combination with standard Western medical care (such as bronchodilators and antibiotics), with the primary goal of reducing hospital stay duration and improving clinical symptoms like cough, phlegm, and breathlessness.

Other names

Modified Maxing Shigan DecoctionMXSGDModified Ma-Xing-Shi-Gan-Tang