Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
modified Qi Ju Di Huang Wan
- Development stage
- Unknown
- Lead developer
- University of Alabama at Birmingham
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Modified Qi Ju Di Huang Wan (mQJDHW) is a multi-herbal traditional Chinese medicine formulation being investigated by the University of Alabama at Birmingham as a liver-targeted therapy for diabetic macular edema (DME). Unlike conventional treatments that focus on local vascular dysfunction in the eye, mQJDHW addresses systemic inflammation and hepatic metabolic dysfunction, which are implicated in the progression of diabetic retinopathy. The formulation consists of twelve components, including *Tribulus terrestris*, *Paeonia lactiflora*, and *Lycium chinensis*. It has been shown to reduce oxidative stress in both the liver and the retina, while providing anti-apoptotic, anti-inflammatory, neuroprotective, and hepatoprotective effects. It is currently being evaluated in a Phase 2 clinical trial, often in combination with the bile acid tauroursodeoxycholate (TUDCA).
- Other names
- Traditional Chinese Medicine (mQJDHW)Modified Qiju Dihuang pill
02
Targets
M1 (Muscarinic acetylcholine receptor M1)ESR1 (ERα)
Beyond the preview
Go deeper on modified Qi Ju Di Huang Wan.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on modified Qi Ju Di Huang Wan.