Drug intelligence / Profile preview

modified renshen yangrong

Development stage
Unknown
Lead developer
Hubei Provincial Traditional Chinese Medical Hospital
Modality
Small Molecules
Administration
Oral
01

Overview

Modified Renshen Yangrong is a Traditional Chinese Medicine (TCM) decoction developed by the Affiliated Hospital of Hubei University of Traditional Chinese Medicine (Hubei Provincial Hospital of TCM). It is a specialized modification of the classic Song Dynasty formula *Renshen Yangrong Tang* (Ginseng Nutritive Decoction). The formula is primarily indicated for Qi deficiency syndrome, characterized by symptoms such as chronic fatigue, shortness of breath, and general physical depletion. In modern clinical practice at the developing institution, it is frequently utilized to manage cancer-related fatigue (CRF) and to support recovery in patients undergoing chemotherapy or surgery. The modification typically involves adjusting the ratios or adding specific herbs to the core components—which include *Panax ginseng*, *Astragalus membranaceus*, and *Angelica sinensis*—to enhance its tonifying effects on the Spleen and Heart and its ability to nourish both Qi and Blood. Research conducted at the Hubei institution suggests that the formula may help regulate immune function, specifically by modulating T-lymphocyte subsets and improving hemoglobin levels in debilitated patients.

Other names
Modified Renshen Yangrong TangJiajian Renshen Yangrong Tang加减人参养荣汤
02

Targets

NOS3 (eNOS)GAA (Lysosomal acid alpha-glucosidase)SLC16A1 (Mitochondrial Pyruvate Carrier)

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