Drug intelligence / Profile preview

modified Wen-Shen Juan-Bi-Tang

Development stage
Unknown
Lead developer
Jiangsu Provincial Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Modified Wen-Shen Juan-Bi-Tang is a Traditional Chinese Medicine (TCM) herbal formula developed by the Jiangsu Province Hospital of TCM for the treatment of ankylosing spondylitis (AS). It is specifically indicated for patients presenting with the TCM syndrome of 'kidney deficiency and coldness in Du Meridian.' The formula is a variation of the classic Wen-Shen Juan-Bi-Tang, which is traditionally used to warm the kidneys, dispel cold, and alleviate joint pain and stiffness. Clinical evaluation of this modified formula, such as in the ChiCTR2000034142 trial, utilizes metabolomics to assess its efficacy in modulating metabolic pathways and reducing systemic inflammation compared to conventional non-steroidal anti-inflammatory drugs (NSAIDs) like celecoxib.

Other names
modified Wenshen Juanbi DecoctionJia-Jian Wen-Shen Juan-Bi-Tang

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