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Modified Wuzi Yanzong Pill is a Traditional Chinese Medicine (TCM) herbal formula developed by the Affiliated Hospital of Shandong University of Traditional Chinese Medicine for the treatment of oligoasthenospermia. It is a variation of the classic Wuzi Yanzong Pill, which traditionally consists of five seeds: *Cuscuta chinensis*, *Lycium barbarum*, *Rubus chingii*, *Schisandra chinensis*, and *Plantago asiatica*. The modified version typically incorporates additional herbs to enhance its kidney-tonifying and essence-replenishing properties. It works by improving sperm concentration, motility, and morphology, likely through mechanisms involving the regulation of the hypothalamic-pituitary-gonadal axis, reduction of oxidative stress in the testes, and improvement of the testicular microenvironment.
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