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Modified yiguanjian granules is a traditional Chinese medicine (TCM) formulation prepared as granules, representing a modified version of the classic TCM formula Yiguanjian. The classic Yiguanjian formula is composed of *Rehmannia glutinosa* (Sheng Di Huang), *Glehnia littoralis* (Bei Sha Shen), *Ophiopogon japonicus* (Mai Dong), *Angelica sinensis* (Dang Gui), *Lycium barbarum* (Gou Qi Zi), and *Melia toosendan* (Chuan Lian Zi). It is traditionally used to nourish yin, benefit the stomach, soothe the liver, and regulate qi. Modified yiguanjian granules are being evaluated in clinical trials, such as those sponsored by the Jiangsu Province Hospital on Integration of Chinese and Western Medicine, for the treatment of chronic atrophic gastritis (CAG) in patients presenting with liver-stomach yin deficiency syndrome.
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