mofebutazone

Mofebutazone is a non-steroidal anti-inflammatory drug (NSAID) of the pyrazolidine class, structurally related to phenylbutazone but lacking one phenyl group. It is primarily used for the treatment of joint and muscular pain. Mofebutazone acts by inhibiting cyclooxygenase (COX) enzyme, thereby reducing prostaglandin synthesis and exerting anti-inflammatory and analgesic effects. The drug also demonstrates antioxidant activity. Compared to phenylbutazone, it has lower toxicity but also weaker analgesic and anti-inflammatory effects. Mofebutazone binds extensively to plasma albumin and can interact with other drugs that bind albumin such as coumarin anticoagulants, indomethacin, and glucocorticoids[1][4][5][6][8].

Other names

monophenylbutazonemophebutazone4-butyl-1-phenylpyrazolidine-3,5-dionemofebutazona