mogroside v

Mogroside V is a natural cucurbitane glycoside and triterpenoid isolated from the fruit of Siraitia grosvenorii (monk fruit). It is intensely sweet—about 250 times sweeter than sucrose—and is widely used as a low-calorie natural sweetener in foods and beverages[1][3][5]. Mogroside V exhibits antioxidant properties and has demonstrated anti-inflammatory, anti-diabetic, and anti-carcinogenic effects in preclinical studies[1][5][7]. In cancer models, it inhibits tumor growth by promoting apoptosis and cell cycle arrest in pancreatic cancer cells as well as inhibiting angiogenesis[1][5]. Recent research also suggests neuroprotective effects; mogroside V can mitigate neurotoxicity and dopaminergic neuron loss in Parkinson’s disease models by restoring metabolic balance in affected brain regions[2]. Its mechanisms include modulation of oxidative stress pathways (e.g. inhibition of COX-2 expression/ROS production) but do not involve direct action on classic drug targets. Mogroside V is primarily developed for use as a food additive or dietary supplement rather than as a pharmaceutical drug.

Other names

MGV88901-36-4ZFF6Z51TURZFF-6Z51TURZFF 6Z51TURUNII-ZFF6Z51TURUNII-ZFF-6Z51TURUNII-ZFF 6Z51TURMOGROSIDE V USP-RS