Drug intelligence / Profile preview

MOH-A5

Development stage
Preclinical
Lead developer
Multiomic Health
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Parenteral
01

Overview

MOH-A5 is a preclinical therapeutic candidate being developed by Multiomic Health in partnership with Alloy Therapeutics for the treatment of chronic kidney disease (CKD). The program specifically targets kidney inflammation and fibrosis across multiple etiologies. MOH-A5 was identified using Multiomic Health's precision medicine platform, which utilizes multi-omics data to stratify patient populations and identify disease-driving mechanisms. As of 2024, the asset is in the in vitro and in vivo validation stage of preclinical development. The partnership with Alloy Therapeutics suggests the drug is likely a human monoclonal antibody discovered via Alloy's ATX-Gx platform.

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