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Drug intelligence / Profile preview
Mol-T
- Development stage
- Phase 4
- Lead developer
- Sanrey Therapeutics
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Mol-T is a fixed-dose combination oral analgesic tablet developed and marketed by Sanrey Therapeutics for the short-term management of moderate to severe pain. It contains tramadol hydrochloride (37.5 mg), an atypical opioid analgesic, and paracetamol (acetaminophen, 325 mg), a non-opioid analgesic and antipyretic. Tramadol provides pain relief by acting as a weak agonist at the mu-opioid receptor and inhibiting the reuptake of serotonin and norepinephrine, while paracetamol acts centrally to inhibit prostaglandin synthesis. This combination offers synergistic pain relief with a rapid onset and prolonged duration of action.
- Brand names
- Mol-TMol-T Tablet
- Other names
- acetaminophen + tramadolparacetamol + tramadoltramadol + acetaminophentramadol + paracetamol
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)MOR (Mu opioid receptor)NET (Norepinephrine Transporter)SERT (Sodium-dependent serotonin transporter)
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