Drug intelligence / Profile preview

MOMB-Ag-NPs

Development stage: Preclinical
Modality: Nanoparticles → Drug Delivery Systems, Small Molecules
Administration: Intraperitoneal

Overview

**MOMB-Ag-NPs** is an experimental, green-synthesized silver-nanoparticle formulation designed to co-deliver methylene blue and *Moringa oleifera* extract for Alzheimer's disease. The formulation uses silver nanoparticles as a carrier intended to improve stability and brain delivery; in P301S tau-transgenic mice, intraperitoneal administration improved behavioral outcomes and was associated with reduced neuroinflammation and astrogliosis, increased antioxidant and autophagy markers, and modulation of AKT/GSK-3β signaling. Its proposed multitarget activity includes inhibition of glycogen synthase kinase-3β and inhibition of tau aggregation, together with antioxidant and anti-inflammatory effects attributed to the botanical extract. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/41455863/))

Other names: MOMB-Ag-NPs

Targets

MAPT (Microtubule-associated protein tau)GSK3 (Glycogen synthase kinase 3 beta)

Beyond the preview

Go deeper on MOMB-Ag-NPs.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on MOMB-Ag-NPs.

Explore the full profile