momordica charantia extract

Momordica charantia extract, commonly known as bitter melon extract, is derived from the fruits of the Momordica charantia plant, which is native to India and other Asian countries, growing in tropical and subtropical regions of Asia, Africa, and the Caribbean. This extract has been traditionally used in various medicinal systems, particularly for managing diabetes and other health conditions. The extract contains several bioactive compounds including charantin (a steroidal saponin with insulin-like properties), polypeptide-p (an insulin-like peptide), vicine, and various phenolic compounds, flavonoids, and triterpenoids[1][6]. These compounds are believed to contribute to its hypoglycemic effects, which have made it popular in traditional medicine for diabetes management[1][2]. The primary mechanism of action appears to be through insulin-like effects that help reduce blood glucose levels. Charantin, one of the main active components, has a molecular weight of 9.7 kDa and chemical properties similar to insulin[6]. The extract may improve glucose tolerance and insulin sensitivity[2]. Traditionally used in various medicinal systems for diabetes management, bitter melon extract has shown moderate hypoglycemic effects in limited clinical studies[2]. Beyond its antidiabetic properties, it has been investigated for potential benefits in treating osteoarthritis, improving athletic performance, and for its antiviral, antineoplastic (anticancer), and immunomodulatory activities[1][2][7].

Brand names

balsam applebalsam pearbitter applebitter cucumberbitter gourdkarelalakwamargosewild cucumber

Other names

bitter melon extractbitter gourd extractkarela extractbalsam pear extractbitter cucumber extract