Drug intelligence / Profile preview

Mondamine DH-1N

Development stage
Unknown
Lead developer
Earth Corporation
Modality
Small Molecules
Administration
Topical
01

Overview

Mondamine DH-1N is a medicated mouthwash developed by Earth Chemical Co. (Earth Corporation) for the management and suppression of dentin hypersensitivity. It is designed to alleviate the sharp, transient pain arising from exposed dentin in response to external stimuli such as cold air, cold water, and mechanical abrasion. The product is part of the Mondamine brand of oral care solutions and has been evaluated in clinical trials to assess its efficacy in reducing pain scores on an 11-point numerical rating scale (NRS). While the specific active ingredients of the DH-1N formulation are often proprietary in early clinical stages, products in the Mondamine sensitivity line typically utilize agents like potassium nitrate to desensitize dental nerves or aluminum lactate to occlude dentinal tubules, thereby preventing the hydrodynamic movement of fluid that triggers pain receptors.

Brand names
Mondamine DH-1N
Other names
Mondamine DH-1N mouthwash

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