Drug intelligence / Profile preview

Morevirin

Development stage
Phase 3
Lead developer
Valenta Pharm
Modality
Small Molecules
Administration
Oral
01

Overview

Morevirin is a small molecule antiviral drug developed by Valenta Pharmaceuticals, containing the active ingredient enisamium iodide. It is approved for the treatment and prophylaxis of influenza and other acute respiratory viral infections (ARVI), including COVID-19. The primary mechanism of action involves the inhibition of viral RNA-directed RNA polymerase (RdRp), which prevents the synthesis of viral RNA and halts replication. Beyond its direct antiviral activity, Morevirin acts as an interferon inducer, enhancing the body's innate immune response by stimulating the production of endogenous interferons. It also provides symptomatic relief through its anti-inflammatory and analgesic properties.

Brand names
MorevirinAmizon
Other names
enisamium iodideenisamiumAmizonum4-(benzylcarbamoyl)-1-methylpyridinium iodide
02

Targets

Influenza A virus RNA-directed RNA polymerase complexRdRp (Coronavirus RNA-dependent RNA polymerase)

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