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moringa leaf extract
- Development stage
- Unknown
- Lead developer
- Umm Al-Qura University
- Administration
- Topical
01
Overview
Moringa leaf extract, derived from the *Moringa oleifera* plant, is a botanical extract being investigated for its regenerative and wound-healing properties in dental applications. Specifically, researchers at Umm al-Qura University are evaluating its efficacy in promoting alveolar socket regeneration and accelerating soft tissue healing following tooth extraction. The extract contains bioactive phytochemicals like kaempferol and exhibits antimicrobial, antioxidant, and anti-inflammatory activities. Its mechanism involves the modulation of pro-inflammatory cytokines such as TNF-α and IL-6, as well as the stimulation of growth factors like VEGF and TGF-β1 to enhance collagen formation and osteoblast activity. In clinical study settings, it is often applied topically in combination with Acemannan and protected by a collagen membrane.
- Other names
- Moringa oleifera leaf extractMoringa extract
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)VEGFA (Vascular endothelial growth factor A)TGFB1 (Transforming growth factor Beta-1 proprotein)
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