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morus alba ethanolic extract
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Morus alba ethanolic extract is a botanical research compound derived from the white mulberry plant (*Morus alba L.*) using ethanol as a solvent. It contains a diverse array of bioactive phytochemicals, including flavonoids such as quercetin, kaempferol, and isorhamnetin, as well as phenolic acids like chlorogenic acid. The extract has demonstrated therapeutic potential in preclinical models for various conditions, including epilepsy (via modulation of GABA-A and 5-HT3A receptors), obesity (through melanin-concentrating hormone-1 receptor antagonism), and diabetes (via AMPK/mTOR-mediated autophagy and pancreatic islet protection). It also exhibits neuroprotective, antioxidant, and antibacterial properties. As a complex botanical extract, its pharmacological profile is attributed to the synergistic effects of its multiple constituents rather than a single active ingredient.
- Other names
- white mulberry ethanolic extractMorus alba L. ethanolic extract
02
Targets
GABA-A receptor α1β2γ2 (GABA_A receptor α1β2γ2 – N-methyllaurotetanine)HTR3A (5-hydroxytryptamine receptor 3A)MCHR1 (Melanin-concentrating hormone receptor 1)
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