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mosapride citrate sustained release
- Development stage
- Phase 3
- Lead developer
- Korea United Pharm
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
UI05MSP015CT is a sustained-release formulation of mosapride citrate developed by Korea United Pharm. Inc. for the treatment of functional dyspepsia. Mosapride is a selective 5-HT4 receptor agonist that enhances gastrointestinal motility by stimulating the release of acetylcholine from enteric cholinergic neurons. Unlike the conventional immediate-release formulation which requires thrice-daily dosing, UI05MSP015CT is designed for once-daily administration, improving patient compliance. It has undergone Phase 3 clinical trials in South Korea comparing its efficacy and safety to the standard thrice-daily mosapride regimen and is currently approved for use in South Korea.
- Brand names
- Gasmotin SRMosalron
- Other names
- mosapride citrate SRmosapride citrate CRonce-daily mosapride
02
Targets
HTR3A (5-hydroxytryptamine receptor 3A)HTR4 (5-Hydroxytryptamine receptor 4)
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