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MEC is a polyherbal mouthwash formulation containing curcumin (0.10% w/v), clove oil (0.15% v/v), and mentha, among other essential oils. It is used as an adjunct to nonsurgical periodontal therapy (scaling and root planing). Curcumin, the primary active component, is a polyphenolic compound from *Curcuma longa* with anti-inflammatory, antioxidant, and antimicrobial properties. The formulation aims to reduce periodontal inflammation and systemic inflammatory markers in patients with chronic periodontitis and rheumatoid arthritis by targeting oral pathogens like *Porphyromonas gingivalis* and reducing levels of C-reactive protein (CRP) and other rheumatoid factors.
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