Drug intelligence / Profile preview

moxifloxacin + artificial tears + dexamethasone + fluorometholone

Development stage
Unknown
Lead developer
Benha University
Modality
Small Molecules
Administration
Ophthalmic, Topical
01

Overview

This conventional treatment regimen was utilized as the control arm in a clinical study sponsored by Benha University to evaluate corneal epithelial healing following photorefractive keratectomy (PRK). The regimen includes the topical fluoroquinolone antibiotic moxifloxacin (0.5%) to prevent post-operative infection, artificial tears (Systane Ultra) for ocular surface lubrication and hydration, and a sequential corticosteroid protocol involving dexamethasone (0.1%) followed by fluorometholone (0.1%) to manage inflammation and prevent corneal haze. This combination represents the standard of care against which experimental therapies like topical insulin and autologous serum were compared.

Brand names
VigamoxSystane UltraMaxidexEfemyo
Other names
Conventional treatment
02

Targets

DNA gyraseTopo IV (Bacterial Topoisomerase IV)GR (Glucocorticoid receptor)

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