moxifloxacin + dexamethasone

Moxifloxacin + dexamethasone is a fixed-dose combination ophthalmic medication used primarily for the treatment of bacterial eye infections and associated inflammation. It combines moxifloxacin, a fourth-generation fluoroquinolone antibiotic, with dexamethasone, a potent synthetic glucocorticoid corticosteroid. Moxifloxacin acts by inhibiting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair in bacteria. This results in bactericidal activity against a broad spectrum of Gram-positive and Gram-negative organisms[6][8]. Dexamethasone exerts anti-inflammatory effects by binding to the glucocorticoid receptor and modulating gene expression to suppress pro-inflammatory mediators such as prostaglandins[3][6]. The combination is indicated for use in ocular conditions where both infection and inflammation are present or suspected[5].

Brand names

MoxigramMilflodexMyticomVigadexaApdrops DMMosi-DFMoxiblu-DMoxicip DMflotas DXMoxoft D

Other names

moxifloxacin + dexamethasone