Drug intelligence / Profile preview

MP-2018

Development stage
Preclinical
Lead developer
Machavert Pharmaceuticals
Modality
Small Molecules
01

Overview

MP-2018 is a small molecule drug developed by Machavert Pharmaceuticals. It acts as an inhibitor of RAL GTPases, a class of small GTP-binding proteins involved in cell signaling pathways that regulate cell proliferation and survival. By inhibiting these targets, MP-2018 is being investigated for its potential antineoplastic (anticancer) effects, particularly in the treatment of non-small cell lung cancer and pancreatic cancer. As of June 2025, the drug remains in preclinical development with no reported clinical trial results or established dosing information[6].

Other names
RAL GTPase inhibitorsMachavert RAL inhibitors
02

Targets

Ral (Ral GTPases)

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