Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
MP5-20F3
- Development stage
- Unknown
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intraperitoneal, Intravenous, Subcutaneous
01
Overview
MP5-20F3 is a rat monoclonal antibody (IgG1, kappa) that specifically binds to and neutralizes mouse interleukin-6 (IL-6). Originally generated at the DNAX Research Institute, this antibody clone is widely utilized as a research-use-only (RUO) reagent for both in vitro and in vivo neutralization of mouse IL-6 bioactivity. It is also commonly employed in laboratory assays such as ELISA, ELISPOT, and flow cytometry. By blocking IL-6, MP5-20F3 inhibits downstream signaling pathways, including the STAT3 pathway, and is frequently used in preclinical mouse models of inflammation, autoimmune disorders, and cancer to investigate the role of IL-6 in disease pathogenesis.
- Other names
- anti-IL-6 antibody clone MP5-20F3anti-IL6 antibody clone MP5-20F3anti-IL 6 antibody clone MP5-20F3anti-mouse IL-6 clone MP5-20F3clone MP5-20F3
02
Targets
IL-6 (Interleukin 6)
Beyond the preview
Go deeper on MP5-20F3.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on MP5-20F3.