Drug intelligence / Profile preview

MPB-1734

Development stage
Phase 2
Lead developer
MegaPro Biomedical
Modality
Small Molecules, Nanoparticles → Drug Delivery Systems
Administration
Intravenous
01

Overview

MPB-1734 is a novel anticancer drug formulation developed by MegaPro Biomedical using their proprietary nanomicelle technology platform. It is a nanoformulation of cabazitaxel, a taxane-based chemotherapeutic agent. The drug works as a tubulin inhibitor, effectively inhibiting tumor growth. The nanomicelle encapsulation enhances drug efficacy through passive targeting that increases drug accumulation at tumor sites while reducing side effects. Preclinical studies have shown that MPB-1734 has outstanding antitumor effects on drug-resistant malignant animal models. When combined with immune checkpoint inhibitors such as anti-PD-1/PD-L1 antibodies, it has demonstrated enhanced tumor suppression in animal studies.

Other names
Cabazitaxel nanoformulationDMB025DMB-025DMB 025
02

Targets

TUBB (Tubulin (alpha and beta subunits))

Beyond the preview

Go deeper on MPB-1734.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on MPB-1734.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call