Drug intelligence / Profile preview

MPFluc-150

Development stage
Unknown
Lead developer
Marriott Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

MPFluc-150 is an oral antifungal medication containing 150 mg of fluconazole, developed and marketed by Marriott Pharmaceutical. As a triazole antifungal, it works by inhibiting the fungal enzyme lanosterol 14α-demethylase (CYP51), a cytochrome P-450 enzyme essential for converting lanosterol to ergosterol. The resulting depletion of ergosterol disrupts the integrity of the fungal cell membrane, exerting a fungistatic effect. It is primarily indicated as a single-dose treatment for vulvovaginal candidiasis (vaginal yeast infection) and is also used for other susceptible fungal infections.

Brand names
MPFluc-150MPFluc150MPFluc 150
Other names
Fluconazole 150 mgFluconazole150 mgFluconazole-150 mg
02

Targets

CYP51A1 (Sterol 14α-demethylase)

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