Drug intelligence / Profile preview

MPL-005

Development stage
Unknown
Lead developer
MediPharm Labs
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

MPL-005 is an investigational **oral cannabis herbal-extract oil** containing cannabidiol and delta-9-tetrahydrocannabinol at a 5:1 CBD:THC ratio. Each mL contains 25 mg cannabidiol and 5 mg delta-9-tetrahydrocannabinol. It is produced by MediPharm Labs and is being evaluated for chronic pain and for symptom-management tolerability in children with cancer. The THC component is a partial agonist of cannabinoid receptors 1 and 2, while cannabidiol has broad, incompletely defined cannabinoid-related pharmacology. ([cdek.pharmacy.purdue.edu](https://cdek.pharmacy.purdue.edu/trial/NCT05754840/))

Other names
5:1 cannabidiol:delta-9-tetrahydrocannabinol oral formulation
02

Targets

CNR2 (Cannabinoid receptor type 2)

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