Drug intelligence / Profile preview

MQ719

Development stage
Unknown
Lead developer
Memorial Sloan Kettering Cancer Center
Modality
Oncolytic Viruses → Oncolytic Therapeutics
Administration
Intratumoral
01

Overview

MQ719 is a multi-transgene expressing Modified Vaccinia Virus Ankara-Based Virotherapy. It is currently under investigation in a Phase 1 clinical trial for the treatment of various solid tumor cancers, including melanoma, metastatic cancer, and head and neck squamous cell carcinoma. The drug is administered via intratumoral injection, and its mechanism involves leveraging a modified virus to potentially induce an anti-tumor immune response. It is being studied both as a monotherapy and in combination with pembrolizumab.

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