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**mRNA-1851** is an investigational mRNA vaccine developed by Moderna for prophylaxis against influenza A H7N9 subtype infections, a strain with pandemic potential. It encodes the hemagglutinin glycoprotein of the H7N9 influenza virus to elicit immune responses, functioning as both a hemagglutinin inhibitor and immunostimulant. The vaccine demonstrated tolerability and strong humoral immunogenicity in early clinical data, advancing as one of Moderna's first mRNA vaccine candidates targeting influenza.[1][4][5][7]
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