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MRS8431
- Development stage
- Unknown
- Lead developer
- National Institutes of Health
01
Overview
MRS8431: sourced facts only. name: "Compound 30 (MRS8431) inhibited ABCG2-ATPase activity with IC50 160 ± 9 nM, while compound 40 (MRS8432) stimulated it potently with EC50 7.5 ± 2 nM." [PMID:41703909]; target: "Compound 30 (MRS8431) inhibited ABCG2-ATPase activity with IC50 160 ± 9 nM, while compound 40 (MRS8432) stimulated it potently with EC50 7.5 ± 2 nM." [PMID:41703909]; developer: "Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, United States." [PMID:41703909]
02
Targets
ABCG2 (Breast cancer resistance protein)
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