Drug intelligence / Profile preview

MRX-801

Development stage
Phase 4
Lead developer
Mirum Pharmaceuticals
Modality
Small Molecules
Administration
Intravenous
01

Overview

MRX-801 is a drug candidate developed by ImaRx Therapeutics as an adjunctive therapy for acute ischemic stroke. It was evaluated in a Phase 1-2, randomized, placebo-controlled, single-blind, dose escalation study to assess its safety, tolerability, and activity when administered with continuous ultrasound as an adjunctive therapy to intravenous tissue plasminogen activator (tPA) treatment. The development of MRX-801 was effectively abandoned after ImaRx Therapeutics ceased operations and underwent a reverse merger.

Brand names
ISPAN C3F8UNIPURE C3F8 Ophthalmic Gas
Other names
perfluoropropaneoctafluoropropaneC3F8C-3F8C 3F81,1,1,2,2,3,3,3-octafluoropropanepropane octafluoro
02

Targets

SLC10A2 (Solute carrier family 10 member 2)SLCO2B1 (Organic anion transporting polypeptide 2B1)

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