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Drug intelligence / Profile preview
MSC-conditioned media gel
- Development stage
- Unknown
- Lead developer
- OCT Therapies and Research
- Administration
- Topical
01
Overview
MSC-conditioned media gel is a cell-free biologic topical gel developed by OCT Therapies and Research for the treatment of oral mucositis associated with cancer therapies. The formulation contains a complex secretome derived from mesenchymal stem cells (MSCs), which includes a variety of growth factors, cytokines, and immunomodulatory molecules. These components work synergistically to modulate the biological milieu of oral lesions, promoting tissue regeneration and wound healing. Currently in Phase 1 clinical development, the drug has demonstrated a favorable safety profile and dose-dependent efficacy in reducing ulcer size and severity in preclinical models.
- Other names
- MSC-CMMSC-derived conditioned media gel
02
Targets
IL10RA (Interleukin-10 Receptor)TGFBR (TGF-beta receptor)VEGFR-1 (Vascular endothelial growth factor receptor 1)IL10 (Interleukin-10)
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