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MT-007
- Development stage
- Preclinical
- Lead developer
- Marigold Therapeutics
- Modality
- Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
MT-007 is a bispecific antibody-drug conjugate (Bs-ADC) currently in the discovery phase of development by Marigold Therapeutics. Designed for the treatment of advanced solid tumors, MT-007 utilizes a bispecific antibody architecture to target two distinct tumor-associated antigens or epitopes. This dual-targeting approach is intended to enhance tumor selectivity, increase the efficiency of receptor-mediated internalization, and potentially overcome resistance mechanisms associated with monospecific ADCs. By delivering a cytotoxic payload directly to malignant cells while sparing healthy tissue, MT-007 aims to provide a superior therapeutic index in the treatment of various solid malignancies.
- Other names
- MT-007 (BIC)
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