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MucoBoost
- Development stage
- Unknown
- Lead developer
- Lovaltech
- Modality
- Recombinant Protein Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Nanoparticles → Drug Delivery Systems
- Administration
- Intranasal
01
Overview
MucoBoost (LVT001) is an intranasal, adjuvant-free protein subunit vaccine developed by Lovaltech in collaboration with the BioMap laboratory (Tours University and INRAE). The vaccine is based on a fusion protein, SwFN, which combines the SARS-CoV-2 Spike protein and Nucleoprotein to elicit a broad-spectrum immune response against multiple viral variants. By utilizing a nanocarrier-based mucosal delivery system, MucoBoost aims to induce local respiratory immunity, potentially blocking both infection and transmission of the virus. It is currently in Phase 2 clinical trials (NCT06821126) for the prevention of COVID-19.
- Brand names
- MucoBoost
- Other names
- LVT001LVT-001LVT 001
02
Targets
FcγR (Fc gamma receptor)SARS-CoV-2 spike
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