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MucoShield
- Development stage
- Preclinical
- Lead developer
- Prime Vector Technologies
- Modality
- Viral Vector Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Intranasal
01
Overview
MucoShield is a preclinical-stage intranasal vaccine developed by Prime Vector Technologies for the prevention of Human Metapneumovirus (HMPV) infection. It utilizes a multivalent antigen design delivered via an Orf virus (ORFV) viral vector platform. The vaccine is specifically designed to activate mucosal immunity at the site of entry, providing a localized defense against HMPV, which is a significant cause of upper and lower respiratory tract infections in children, the elderly, and immunocompromised individuals. By utilizing the ORFV vector, MucoShield aims to induce both robust mucosal and systemic immune responses without the need for traditional adjuvants.
- Brand names
- MucoShield
02
Targets
HMPV F (Human metapneumovirus fusion protein)
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