Drug intelligence / Profile preview

Mudan Granule

Development stage
Unknown
Lead developer
Shanxi Buchang Pharmaceutical
Administration
Oral
01

Overview

Mudan Granule is a Traditional Chinese Medicine (TCM) product developed and manufactured by Shanxi Buchang Pharmaceutical. It is approved in China for the treatment of diabetes and its associated complications, specifically diabetic peripheral neuropathy (DPN). The formulation is a complex mixture of botanical extracts, including *Paeonia suffruticosa* (Mudanpi), *Astragalus membranaceus*, *Salvia miltiorrhiza*, and *Corydalis yanhusuo*. Mudan Granule is designed to improve blood microcirculation, reduce oxidative stress, and provide neuroprotective effects. In clinical practice, it is used to alleviate symptoms such as numbness, pain, and sensory abnormalities in the extremities of diabetic patients. Pharmacological studies suggest that its mechanism involves the inhibition of aldose reductase activity and the modulation of inflammatory pathways associated with chronic hyperglycemia.

Brand names
Mudan Granule
Other names
Mudan KeliMudanpi Granule
02

Targets

AR (Adrenergic receptors)

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