mulberry leaf extract + berberine + cinnamon bark powder + cinnamon bark essential oil

This is a combination dietary supplement containing **mulberry leaf extract**, **berberine** (often as berberine HCl), **cinnamon bark powder**, and **cinnamon bark essential oil**. The combination is formulated to support healthy blood sugar levels, often marketed for the management of glycemic variability in people with type 2 diabetes or prediabetes. - **Mulberry leaf extract** contains 1-deoxynojirimycin (DNJ), which inhibits intestinal enzymes involved in carbohydrate digestion, leading to reduced glucose absorption and attenuated postprandial blood sugar spikes. - **Berberine** is an isoquinoline alkaloid that activates AMP-activated protein kinase (AMPK), inhibits hepatic gluconeogenesis, increases insulin sensitivity, and improves glucose uptake. - **Cinnamon bark powder and essential oil** are rich in polyphenolic compounds that enhance insulin signaling, slow gastric emptying, and reduce the rate of carbohydrate absorption, contributing to blood glucose regulation. Clinical studies of related combinations (e.g., berberine + cinnamon) show significant reductions in fasting blood sugar (FBS), hemoglobin A1C (HbA1c), and LDL cholesterol in patients with type 2 diabetes after 12 weeks of supplementation. The combination is designed to synergistically target multiple metabolic pathways to optimize glycemic control and insulin function[4][6][7][8].

Brand names

MetaPWR AssistMetaPWR Metabolic Assist

Other names

mulberry leaf extract + berberine hydrochloride + cinnamon bark powder + cinnamon bark essential oil