Drug intelligence / Profile preview

mulberry leaf extract + white kidney bean extract + cinnamon

Development stage
Preclinical
Lead developer
Plexus Worldwide
Modality
Small Molecules
Administration
Oral
01

Overview

A dietary supplement combination containing **mulberry leaf extract**, **white kidney bean extract**, and **cinnamon**. This blend is marketed to support healthy blood sugar metabolism and insulin balance. Mulberry leaf extract, standardized for 1-deoxynojirimycin, is believed to reduce dietary sugar and carbohydrate absorption by inhibiting carbohydrate-digesting enzymes in the gut. White kidney bean extract acts as an alpha-amylase inhibitor, also contributing to reduced breakdown and absorption of carbohydrates, thus potentially lowering post-meal glycemic spikes. Cinnamon (typically Cinnamomum cassia bark extract) may enhance the body's insulin sensitivity and glucose metabolism, with effects attributed to its polyphenol content. The combination, often formulated in capsule form, is consumed orally, typically prior to carbohydrate-containing meals, to assist in maintaining stable blood glucose levels. These supplements are widely available, produced by multiple manufacturers, but are not recognized as pharmaceutical drugs or approved to treat, cure, or prevent any disease by major regulatory bodies[1][2][5][6].

02

Targets

AMY (Pancreatic alpha-amylase)Sucrase-Isomaltase

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