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The multivalent COVID-19 inactivated vaccine is a candidate developed by the Beijing Institute of Biological Products (BIBP), a subsidiary of Sinopharm (CNBG). This vaccine utilizes inactivated whole-virus particles from multiple strains or variants of the SARS-CoV-2 virus to induce a broad neutralizing antibody response and protective immunity. As an inactivated vaccine, the virus is typically grown in Vero cell cultures and then chemically inactivated, preserving the structural integrity of the viral antigens (such as the spike, nucleocapsid, envelope, and membrane proteins) to stimulate the immune system without the risk of viral replication. This multivalent approach is intended to provide enhanced protection against emerging variants of concern compared to original monovalent formulations. It is currently in the preclinical/development stage.
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