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This specific multivitamin formulation was developed by the research pharmacy at Al-Hadba University in Mosul to serve as a placebo in a randomized, double-blind clinical trial. The trial evaluated the efficacy of oral melatonin in reducing the duration of excessive crying and infantile colic in neonates. The multivitamin was specifically engineered to match the taste, viscosity, and color of the melatonin drops to ensure effective blinding of the study participants and investigators. While multivitamins are typically used as dietary supplements, this formulation functions as a comparator arm in a clinical setting for neonatal behavioral and gastrointestinal symptoms.
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