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mumps live attenuated vaccine
- Development stage
- Unknown
- Lead developer
- Chinese Academy of Medical Sciences
- Modality
- Live Attenuated Vaccines → Live Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Subcutaneous[6][8]
01
Overview
The mumps live attenuated vaccine is a prophylactic biological product containing weakened (attenuated) strains of the mumps virus. It is designed to stimulate an immune response that confers protection against future infection by wild-type mumps virus. The attenuation process reduces the virulence of the virus while maintaining its immunogenicity. The most common production method uses primary chicken embryo fibroblasts as cell substrates, though some newer versions use human diploid cells[5][7]. In China and globally, both monovalent (mumps only) and combination vaccines (such as MMR or measles-mumps combined vaccines) are available[1][6][8]. The mechanism of action involves induction of humoral and cellular immunity against the mumps virus through exposure to viral antigens without causing disease[6][7]. Primary indication is prevention of epidemic parotitis (mumps).
- Other names
- 腮腺炎减毒活疫苗mumps vaccinelive attenuated mumps vaccineF-genotype mumps live attenuated vaccine
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