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Drug intelligence / Profile preview
murine A10 MAb
- Development stage
- Preclinical
- Lead developer
- Kobe University
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
murine A10 MAb is a parental murine monoclonal antibody directed against carcinoembryonic antigen (CEA), also known as CEACAM5. Developed by researchers at Kobe University, the antibody specifically binds to CEA, a cell-surface glycoprotein that is highly expressed in various gastrointestinal cancers, including pancreatic carcinoma. In preclinical studies, murine A10 MAb and its recombinant mouse-human chimeric Fab fragments have been evaluated for their potential in the radioimmunodetection (imaging) and radioimmunotherapy of pancreatic and other gastrointestinal tumors.
- Other names
- A10 MAbA-10 MAbA 10 MAbA10 monoclonal antibodyA-10 monoclonal antibodyA 10 monoclonal antibodyanti-CEA monoclonal antibody A10anti-carcinoembryonic antigen monoclonal antibody A10murine A10 monoclonal antibody
02
Targets
CEACAM5 (Carcinoembryonic antigen related cell adhesion molecule 5)
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