Drug intelligence / Profile preview

murine interleukin-2

Development stage
Preclinical
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes
Administration
Intraperitoneal, Intravenous (in Mouse Studies), Local Implantation (as Genetic Or Cellular Therapy In Mouse Models)
01

Overview

**Murine interleukin-2** is the mouse (murine) form of the cytokine interleukin-2 (IL-2), a naturally occurring signaling protein that plays a crucial role in the regulation and activation of immune responses, particularly the proliferation and activation of T cells and natural killer (NK) cells. In research and preclinical studies, murine IL-2 is frequently used to model and investigate immune responses in mice, since it specifically interacts with the mouse IL-2 receptor system and demonstrates distinct pharmacological properties compared to human IL-2[2]. Murine IL-2 has applications in basic immunology research, cancer immunotherapy studies in mouse models, and the development and testing of cytokine-based therapies targeting tumor growth and immune regulation[2][7]. It is not used as a pharmaceutical drug in humans.

Other names
mouse interleukin-2muIL-2muIL2muIL 2IL-2 (mouse)
02

Targets

IL2RB (IL-2 receptor beta chain)IL2RG (Interleukin-2 receptor gamma subunit)IL2RA (Interleukin-2 receptor alpha subunit)

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