Drug intelligence / Profile preview

murraya koenigii

Development stage
Unknown
Lead developer
Orgenetics
Modality
Small Molecules
Administration
Oral, Topical, Trunk Injection
01

Overview

Murraya koenigii, commonly known as the curry tree, is a medicinal plant native to South Asia belonging to the Rutaceae family. Its leaves and stems are rich in bioactive carbazole alkaloids (such as mahanimbine, girinimbine, and koenimbine), flavonoids, and terpenoids, which confer antioxidant, anti-inflammatory, antimicrobial, and antidiabetic properties. The plant is utilized in various forms, including powdered leaves, methanolic or ethanolic extracts, and specialized formulations like the plant-based iron supplement Orgen-I. Clinical and preclinical research has investigated its efficacy in treating iron deficiency anemia, irritable bowel syndrome (IBS), non-alcoholic steatohepatitis (NASH), and metabolic disorders. Additionally, Murraya koenigii extracts are employed in green chemistry for the synthesis of nanoparticles and as phytobiotics in aquaculture and livestock to enhance growth and disease resistance.

Brand names
Orgen-I
Other names
curry leafcurry treeMKMurraya koenigii (L.) Spreng
02

Targets

NF-κBGtf (Streptococcus mutans glucosyltransferase)Mpro (3C-like proteinase of SARS-CoV-2)

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