Drug intelligence / Profile preview

MuscleCare

Development stage
Phase 4
Lead developer
MuscleCare
Modality
Small Molecules
Administration
Topical
01

Overview

MuscleCare is a topical analgesic formulation designed for the management of musculoskeletal pain, specifically targeting conditions like myofascial pain syndrome and trapezius trigger points. Developed as an all-natural alternative to traditional non-steroidal anti-inflammatory drug (NSAID) topicals, it typically combines active counter-irritants such as menthol and camphor with supportive ingredients like methylsulfonylmethane (MSM), glucosamine, and chondroitin. The mechanism of action involves the stimulation of sensory receptors (TRPM8 and TRPV1) to provide a cooling or warming sensation that masks deeper pain signals, while ingredients like MSM may offer localized anti-inflammatory benefits. It has been evaluated in clinical trials against standard treatments like diclofenac (Voltaren) for efficacy in relieving trigger point pain.

Brand names
MuscleCareMuscleCare Pain Relief Therapy
02

Targets

TRPA1 (Transient receptor potential cation channel subfamily A member 1)TRPV1 (Transient receptor potential cation channel subfamily V member 1)TRPV3 (Transient receptor potential vanilloid subtype 3)Muscle-type nicotinic acetylcholine receptor

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