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MusCool Spray
- Development stage
- Unknown
- Lead developer
- Chao Phya Abhaibhubejhr Hospital
- Administration
- Topical
01
Overview
MusCool Spray is a topical herbal analgesic and anti-inflammatory spray developed by the Chaopraya Abhaibhubejhr Hospital in Thailand. It is primarily formulated with the essential oil of *Zingiber cassumunar* (commonly known as Plai), a plant traditionally used in Thai medicine for musculoskeletal ailments. The active components of the oil, such as (E)-1-(3,4-dimethoxyphenyl)butadiene (DMPB), exert their therapeutic effects by inhibiting the cyclooxygenase (COX) and lipoxygenase (LOX) pathways, which reduces the production of pro-inflammatory prostaglandins and leukotrienes. The spray is designed to provide a cooling sensation and rapid localized relief for muscle pain, sprains, and inflammatory conditions without the need for vigorous rubbing.
- Brand names
- MusCool Spray
- Other names
- Plai sprayZingiber cassumunar spray
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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